Beauty series
Collagen Tripeptida
- Collagen in food is a chain made up of up to 3000 units of amino acids, but they are too big to be absorbed
- Collagen Tripeptide (CPT) is the minimum unit of collagen compound composed of 3 amino acids.
Clinically Proven Efficacy
- Ina vivo study, male rats were administered 0.35 mmol/kg of Gly- Pro- Hyp (major components of CTP- containing collagen) and Proline (an amino acid) respectively.
- Its result showed that CTP was detected in plasma 5 minutes after administration and it was absorbed more quickly than proline.
- The results indicated that CTP was absorbed into the blood vessel more quickly and effectively than amino acids.
- The production of hyaluronic acid up to 1.5 times as a result of adding CTP which effect is more than that of N- acetylglucosamine (GlcNAc).
- CTP- containing collagen had higher promotion effect on collagen synthesis on dermis than that of other test samples.
- CTP containing collagen helped in reducing damage skin like wrinkle formation caused by UV.
Purple Chrysanthemum
Edible Purple Chrysanthemum (ENMEIRAKU)
- Edible Purple Chrysanthemum also known as Enmeiraku
- It was traditionally eaten in Japan and China for food or pharmaceutical use for perpetual youth and longevity
- Enmeiraku possesses various functional ingredients especially polyphenols such as luteolin, chlorogenic acid and anthocyanin which possess strong anti-glycation activity.
Anti-Glycatio
- Glycation is the natural phenomenon that involved bonding of proteins and sugar within the body
- However, Advanced Glycation End Products (AGEs) produced by glycation can bring various symptoms
- Accumulation of AGEs can lead to different symptoms:
- Alzheimer’s disease
- Arteriosclerosis
- Diabetes complications
- Aging of skin
- Collagen Crosslink
- Osteoporosis, Osteoarthropathy
Enmeiraku was tested to have higher anti-glycemic effect compared to yellow chrysanthemum and aminoguanidine hydrochloride (An anti-glycation agent)
Activity is stronger with smaller value
Clinically Proven Efficacy
Antioxidant activity of the purple chrysanthemum (Enmeiraku)
A study showed that Enmeiraku to have strongest antioxidant activity when compared to onion, parsley and green powdered tea which are known for their antioxidant activity. The results showed that Enmeiraku gave highest ORAC value and hydroxyl radical elimination activity.
Skin Improvement
A double- blind, randomized, controlled trial was conducted on 35 women who demonstrated low R2 skin elasticity index and high AGEs- derived fluorescence intensity up to 8 weeks. They were divided into 3 groups (placebo, low dose group, high dose group). Enmeiraku group had decrease in melanin, hidden spots, enhanced elasticity, inhibition of progression of erythema and smoothness of spores.
Yeast Ceramide
- Ceramides are major component of skin’s surface. However, ceramide production declines as aging and skin begins to sag and wrinkle.
CLINICALLY PROVEN EFFICACY
In an animal study to determine the effect of plant and yeast cerebrosides on melanin formation.
Result:
- Yeast cerebroside were found to significantly suppress the formation of melanin to the level similar to arbutin (skin lightening agent).
- Cerebrosides derived from plant source showed no suppressive effect.
- Cerebrosides from bovine brain induced an increase of almost 1.2- fold melanin formation compared to control.
Conclusion:
Melanin formation is regulated by cerebrosides containing 9- methyl- type sphingoid base such as yeast cerebrosides. Thus, yeast cerebroside is capable of suppressing melanin formation.
